Assessing Blood Brain Barrier Dynamics or Identifying or Measuring Selected Substances, including Ethanol or Toxins, in a Subject by Analyzing Raman
نویسنده
چکیده
4,731,726 A 3/1988 Allen, I11 et al. 5,243,983 A 9/1993 Tarr et al. 5,291,560 A 3/1994 Daugman . 5,308,356 A 5/1994 Blackshear, 5,336,970 A 8/1994 Einbinder 5,377,681 A 1/1995 Drane ..... 5,433,197 A 7/1995 Stark .......................... 128/633 5,471,203 A 11/1995 Sasaki et al. 5,521,392 A 5/1996 Kennedy et a 5,535,743 A 7/1996 Backhaus et al. ........... 128/633 5,553,617 A * 9/1996 Barkenhagen .............. 600/318 5,553,743 A 9/1996 Thompson et al. ............ 222/52 5,572,596 A 11/1996 Wildes et al. ............... 382/117 5,613,012 A 3/1997 Hoffman et al. ............ 382/115 5,615,277 A 3/1997 Hoffman .................... 382/115 5,666,956 A 9/1997 Buchert 5,710,630 A 1/1998 Essenpre 5,882,301 A 3/1999 Yaoshida 6,119,096 A 9/2000 Mann et al. 6,181,957 B1 1/2001 Lambert et a 6,205,354 B1 3/2001 Gellerman et al. 6,223,069 B1 4/2001 Pfeiffer et al. 6,312,686 B1 11/2001 Staddon et al. 6,574,501 B2 * 6/2003 Lambert et al. ............. 600/473 6,961,599 B2 * 11/2005 Lambert et al. 600/3 18 2001/0032098 A1 10/2001 Kulkarni 2002/0049389 A1 * 4/2002 Abreu ........................ 600/558
منابع مشابه
Toxins in a Subject by Analyzing Raman Spectrum Signals of Selected Regions in the Eye
Also, non-invasive methods for determining the brain or blood level of an analyte of interest, such as glucose, drugs, alcohol, poisons, and the like, comprises: generating an excitation laser beam (e.g., at a wavelength of 600 to 900 nanometers); focusing the excitation laser beam into the anterior chamber of an eye of the subject so that aqueous humor, vitreous humor, or one or more conjuncti...
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Also, non-invasive methods for determining the brain or blood level of an analyte of interest, such as glucose, drugs, alcohol, poisons, and the like, comprises: generating an excitation laser beam (e.g., at a wavelength of 600 to 900 nanometers); focusing the excitation laser beam into the anterior chamber of an eye of the subject so that aqueous humor, vitreous humor, or one or more conjuncti...
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Background: Nitric oxide synthase (NOS) activity is increased during hypertension and cerebral ischemia. NOS inactivation reduces stroke-induced cerebral injuries, but little is known about its role in blood-brain barrier (BBB) disruption and cerebral edema formation during stroke in acute hypertension. Here, we investigated the role of NOS inhibition in progression of edema formation and BBB d...
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Introduction: Arterial hypertension is one of the causes of stroke, and as one of the vasculotoxic conditions intensifies ischemic stroke complications. The aim of the present study was to analyze the effects of short-term cerebral hypertension on ischemia/reperfusion injury and pathogenesis of ischemic stroke. Methods: The experiments were performed on three groups of rats (N=36) Sham, cont...
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Introduction: Development of brain edema following focal cerebral ischemia exacerbates primary ischemic injury. Blood brain barrier (BBB) opening is an important part of edema named as vasogenic brain edema. In this study, quantitative alterations of BBB permeability is experimentally evaluated using transient focal cerebral ischemia in the rat. Methods: Two groups of male rats (ischemic and sh...
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